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Wednesday, May 20, 2020 | History

2 edition of Effect of a carcinogenic hydrocarbon on manifest malignant tumors in mice. found in the catalog.

Effect of a carcinogenic hydrocarbon on manifest malignant tumors in mice.

S. Stamer

Effect of a carcinogenic hydrocarbon on manifest malignant tumors in mice.

Eradication of transplanted leukemia in mice and attempts at inhibition of other manifest malignant tumors in mice by treatment with 9 : 10-dimethyl- 1 : 2-benzanthracene.

by S. Stamer

  • 244 Want to read
  • 18 Currently reading

Published by E. Munksgaard, H. Milford, Oxford University Press in Copenhagen, London .
Written in English

    Subjects:
  • Cancer.,
  • Benzanthracenes.

  • Edition Notes

    Other titlesA carcinogenic hydrocarbon.
    Statement(With a summary in Danish) By S. Stamer.
    ContributionsAndersen, Hans, 1880- tr.
    Classifications
    LC ClassificationsRC262 .S8
    The Physical Object
    Pagination158 p. incl. tables, diagrs.
    Number of Pages158
    ID Numbers
    Open LibraryOL6498566M
    LC Control Number46005687
    OCLC/WorldCa10272310

      (, June 27). Scientists decode how anthrax toxin proteins might help treat cancerous tumors: Studies in mice reveal novel treatment regimen. ScienceDaily. Retrieved Ap from www. Tobacco use has predominantly negative effects on human health and concern about health effects of tobacco has a long history. Research has focused primarily on cigarette tobacco smoking.. Tobacco smoke contains more than 70 chemicals that cause cancer. Tobacco also contains nicotine, which is a highly addictive psychoactive tobacco is smoked, .

      Data from in vivo and in vitro studies suggest that activation of Akt regulates cell survival signaling and plays a key role in tumorigenesis. Hence, transgenic mice were created to explore the oncogenic role of Akt1 in the development of mammary tumors. The transgenic mice were generated by expressing myristoylated-Akt1 (myr-Akt1) under the control of the MMTV Cited by: 5. Use of laboratory animals to identify carcinogenic potential of chemicals, mixtures, and other agents has a modern history of greater than 40 years from which much useful scientific and public health information can be derived. While laboratory animals differ from humans in some respects that may affect responses to hazardous exposures, use of such.

      Twenty-one anti-cancer drugs have been tested for their ability to cause mutations in Salmonella typhimurium test strains in the Salmonella/microsome mutagenicity test. Nine of the 21 anticancer drugs showed this ability: cyclophosphamide, nitromin, thio-tepa, busulfan, 6-mercaptopurine, neocarzinostatin, daunomycin, adriamycin and estramustine by: Both viruses and carcinogenic chemicals can cause tumors by slowing cellular growth disruption of cell division creating new cellular genes killing cells Get more help from Chegg Get help now from expert Biology tutors.


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Effect of a carcinogenic hydrocarbon on manifest malignant tumors in mice by S. Stamer Download PDF EPUB FB2

Author(s): Stamer,S Title(s): Effect of a carcinogenic hydrocarbon on manifest malignant tumors in mice. Eradication of transplanted leukemia in mice and attempts at inhibition of other manifest malignant tumors in mice by treatment with dimethylbenzanthracene.

To assess the effects of single polycyclic aromatic hydrocarbons (PAHs) on solid tumor initiation, and investigate their roles in immune response () were randomly divided into 5 groups (n=20) to be intraperitoneally injected with 10 Cited by:   Histopathological analysis of mice.

Figure 2 shows the results relative to the histopathological analysis of the lung, kidney and urinary bladder in terms of incidence, and provides examples of histopathological appearance of the lesions are shown next to each graph.

The time-related and cumulative dose-dependent multiplicity of lung microadenomas, Cited by: 1. Effect of a Carcinogenic Hydrocarbon on Manifest Malignant Tumors in Mice. Munksgaard, Copenhagen. Strong, L.C. The establishment of the "A" strain of inbred mice.

Hered. See also MGI. Strong, L.C. A genetic analysis of the induction of tumors by methylcholanthrene, with a note on the origin of the NH strain of. Abstract. In this study, we investigated the carcinogenic response of transgenic mice carrying the human prototype c-Ha-ras gene, namely Tg rasH2/CB6F1 mice, to various genotoxic carcinogens and compared it with that of control non-transgenic CB6F1 mice (non-Tg mice).The present studies were conducted as the first step in the evaluation of the Tg Cited by: 1 The Laboratory Mouse 1 Joan Staats.

Mus musculusLinn. the common house mouse, has been a member of man's immediate environment for many with other members of the order Rodentia, rats and mice constituting the family Muridae spread with man and his commerce from their origin in Asia to all parts of the world.

ENVIRONMENTAL RESEA () The Carcinogenic Effect of a Series of Petroleum-Derived Oils on the Skin of Mice D. GRADISKI,* J. VINOT,* D. ZISSU,* J.

LIMASSET,f AND M. LAFONTAINEt With the technical assistance of A. Blachere* Services* Toxicologie Industrielle Experimentale et tChimie Toxicologique, Intitut National de Recherche Cited by: A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text.

Full Length Report Oral Methotrexate in Mice: A Co-Carcinogenic as Well as an Anti-Tumor Agent to Methylcholanthrene-Induced Cutaneous Tumors* * From the Clinical Laboratories, Jewish Hospital, Cincinnati and the Departments of Dermatology and Pathology, College of Medicine, University of Cincinnati, Cincinn by: Tumors which are between slow growing and unlikely to spread, and fast growing and likely to spread are called Intermediate tumors If its a benign tumor, it ends with a ___, if its a malignant tumor it ends with a ___.

J. COOK1 pointed out that the sterols and bile acids contain in their molecules condensed carbon-ring systems to which are attached a side-chain in such a position that a new 6-membered ring Cited by:   Carcinogenic effect of a carcinogen administered repeatedly to animals with induced tumors.

Savinskaya Bulletin of Experimental Biology and Medicine vol pages – ()Cite this articleAuthor: A. Savinskaya. Morphology of Mammary Tumors in Mice Thelma B. Dunn VALUE OF MAMMARY TUMORS IN CANCER RESEARCH A most significant event in experimental cancer research, which marked its real beginning, was the publication of Jensen’s work in a He p&formed the first successful serial transplantation of a mammary tumor in the mouse, andFile Size: 6MB.

Cannabis extract and radiation therapy have been found to be an extremely effective combination in treating brain cancer, virtually shrinking the tumors to nothing, according to a new mouse study Author: Traci Pedersen.

Induction of persistent estrus increased the incidences of ovarian tumors and of malignant tumors of the uterus. Treatment with BrdUrd also increased the carcinogenic effect of X-rays on the.

Apo2L/TRAIL has considerable promise for cancer therapy based on the fact that this member of the tumor necrosis factor family induces apoptosis in the majority of malignant cells, while normal cells are more resistant.

Furthermore, in many cells, when Apo2L/TRAIL is combined with chemotherapy, the effect is synergistic. The majority of this work has been Cited by: mice also demonstrate an extremely low incidence of spontaneous tumors, with no indication of pre-neoplastic cell stages or tumors until the age of 6 months.

They are also proven to provide much more rapid onset and a higher incidence of more malignant tumors after being treated with mutagenic or nonmutagenic Size: KB. Fortunately, most tumors in rats are benign. In nine years I've done surgery on about rats to remove tumors, and only a few have been malignant.

Of all these rats, I've removed tumors from only five males; the rest were females, almost all of them with benign mammary tumors.

I've had a very high success rate removing this type of tumor. Malignant tumors Usually made up of undifferentiated non functional cells that do not appear organized.

The cells tend to reproduce more rapidly than. Results - Mice A. Body Weights and Clinical Signs (Mice) B. Survival (Mice) C. Pathology (Mice) D. Statistical Analyses of Results (Mice) V. Discussion VI. Conclusion VII. Bibliography 55 TABLES Table 1 Specifications and Sources of Materials Used for Animal Maintenance 5.

Table 2 Dosage and Survival of Rats and. Malignancy of tumors occurs as a result of the influence of harmful conditions, when cancer cells begin to change and there is: melanoma (melanoblastoma), sarcoma (including liposarcoma, lymphosarcoma and fibrosarcoma), epithelioma.

The intermediate group of pretumor states includes: leukoplakia, cutaneous horn; senile keratoma; basal cell.Lung tumors in strain a mice: Application for studies in cancer chemoprevention. Gary D. Stoner PhD. Corresponding Author. several classes of chemical carcinogens and has been used extensively as a mouse lung tumor bioassay for assessing the carcinogenic activity of a .An essay "Cancer Abnormal Production: Types of Malignant Tumors" claims that Neoplasm is defined by Willis as “Abnormal mass of tissue, the growth of which StudentShare Our website is a unique platform where students can share their papers in a matter of giving an example of the work to be done.